Biomolecules Question 85
Question: Ammonia is very toxic to brain cells. This is immediately trapped in brain by one of the following mechanisms.
Options:
A) Glutamine synthetase reaction
B) Glutaminase reaction
C) Urea synthesis cycle
D) Glutamate dehydrogenase reaction
Show Answer
Answer:
Correct Answer: A
Solution:
[a] Glutamine synthetase catalyses the reaction, glutamic acid + ammonia $ \to $ glutamine; this traps the ammonia in brain.
Glutaminase catalyses the reverse reaction, glutamine $ \to $ glutamic acid + ammonia.
Urea cycle is takingplace in liver.
Glutamate dehydrogenase removes ammonia from glutamic acid, and this is taking place in liver.