Biomolecules Question 85

Question: Ammonia is very toxic to brain cells. This is immediately trapped in brain by one of the following mechanisms.

Options:

A) Glutamine synthetase reaction

B) Glutaminase reaction

C) Urea synthesis cycle

D) Glutamate dehydrogenase reaction

Show Answer

Answer:

Correct Answer: A

Solution:

[a] Glutamine synthetase catalyses the reaction, glutamic acid + ammonia $ \to $ glutamine; this traps the ammonia in brain.

Glutaminase catalyses the reverse reaction, glutamine $ \to $ glutamic acid + ammonia.

Urea cycle is takingplace in liver.

Glutamate dehydrogenase removes ammonia from glutamic acid, and this is taking place in liver.