Biotechnology And Its Applications Question 55
Question: In the treatment of SCID, cDNA is introduced into a patient’s cells using………….as a vector.
Options:
A) E coli
B) Retrovirus
C) Bacillus thuringiensis
D) Agrobacterium
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Answer:
Correct Answer: B
Solution:
[b] A functional ADA (cDNA) can be introduced into cells of the patients receiving gene therapy by using vector constituted by retrovirus.
The SCID patient has a defective gene for the enzyme Adensosine Deaminase (ADA).
He/she lacks functional T-lymphocytes which are extracted from the patient’s bone marrow and a normal functional copy of human gene coding for ADA is introduced into these lymphocytes with the help of retrovirus.
BETA
