Human Health And Disease Question 78

Question: Antigen binding site in an antibody is found between?

Options:

A) One heavy and one light chain

B) Two light chains

C) Two heavy chains

D) Both B and C depending upon nature of antigen

Show Answer

Answer:

Correct Answer: C

Solution:

The correct option is C One heavy and one light chain

Antigen binding site, also known as paratope is a part of an antibody which recognizes and binds to an antigen. It is a small region of 5 to 10 amino acids of the antibody’s Fv region, part of the fragment antigen-binding (Fab region), and contains parts of the antibody’s heavy and light chains. Paratope is present in each arm of Y-shaped antibody between one heavy chain and one light chain.

So, the correct answer is ‘One heavy and one light chain’.