Principle Of Inheritance And Variation Question 175

Question: Assertion : UAA, UAG and UGA terminate protein synthesis. Reason : They are not recognised by tRNA.

Options:

A) If both the assertion and the reason are true and the reason is a correct explanation of the assertion

B) If both the assertion and reason are true but the reason is not a correct explanation of the assertion

C) If the assertion is true but the reason is false

D) If both the assertion and reason are false

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Answer:

Correct Answer: A

Solution:

Synthesis of polypeptide terminates when a nonsense codon of mRNA reaches the A - site.

There are three nonsense codons - UAA, UAG and UGA.

These codons are not recognised by any of the tRNAs.

Therefore, no more aminoacyl tRNA reaches the A- site.

The P-site tRNA is hydrolysed and the completed polypeptide is released in the presence of release factor.

Thus termination occurs.