Principle Of Inheritance And Variation Question 371
Question: Which of the following is not a hereditary disease?
Options:
A) Cystic fibrosis is a genetic disorder that affects the lungs, pancreas, and other organs. It causes thick, sticky mucus to build up in the lungs and obstruct the pancreas, leading to chronic lung infections and digestive problems. The disease is caused by mutations in the CFTR gene, which regulates the movement of salt and water in and out of cells. Cystic fibrosis is inherited in an autosomal recessive pattern, meaning a person must inherit two defective copies of the CFTR gene, one from each parent, to have the disease.
B) Thalassemia
C) Haemophilia
D) Cretinism
Show Answer
Answer:
Correct Answer: D
Solution:
Cystic fibrosis: It is a common disorder among Caucasians in which thick and more salty mucus blocks the respiratory tract.
The homozygous recessive condition results in the defective protein which regulates chloride transport channels.
Cretinism: In this disorder, the physical growth, mental growth and sexual growth in children is retarded.
Such a dwarf and sterile child is called a goiter.
It is due to hyposecretion of thyroid hormones.
Thalassemia: Due to defective production of α or β chains haemoglobin, autosomal recessive.
Haemophilia: Sex linked disorder due to defective recessive gene.
BETA
