Principle Of Inheritance And Variation Question 405

Question: Haemophilia is mentioned as a trait carried by the mother and passed to her sons. What is the pattern of inheritance for this trait?

Options:

A) Haemophilia is an allele carried on one of the mother’s autosomal chromosomes.

B) Haemophilia is an allele carried on the Y chromosome because more males have this genetic disorder than females.

C) Haemophilia is an allele carried on the X chromosome and can be directly inherited by the son from the father or the mother.

D) Haemophilia is carried on the X chromosome and can only be inherited by the son if the mother is a carrier.

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Answer:

Correct Answer: D

Solution:

[d] Haemophilia is an X-linked trait, and can only be inherited by the son from his mother’s X chromosome.

The father contributes the Y chromosome to his son (not his X chromosome) and thus, cannot pass any of his X-linked alleles to his son.