Principle Of Inheritance And Variation Question 410

Question: Match column-I with column-II and select the correct option from the codes given below.

Column-I Column-II A. Autosomal recessive trait I. Down?s syndrome B. Sex-linked recessive trait II. Phenylketonuria C. Metabolic error linked to autosomal recessive trait III. Haemophilia D. Additional 21st chromosome IV. Sickle cell anaemia

Options:

A) A-II; B-I; C-IV; D-III

B) A-IV; B-I; C-II; D-III

C) A-IV; B-III; C-II; D-I

D) A-III; B-IV; C-I; D-II

Show Answer

Answer:

Correct Answer: C

Solution:

[c] Sickle cell anaemia is an autosomal recessive trait.

Haemophilia is a sex linked recessive trait.

Metabolic error is linked to autosomal recessive: Phenylketonuria is an inherited disease due to faulty metabolism of phenylalanine.

The affected individual lacks an enzyme that converts the amino acids phenylalanine into tyrosine.

It is characterised by the presence of phenylketones in the urine and usually first noted by signs of mental retardation in infancy.

Down’s syndrome occurs due to presence of an additional 21st chromosomes.



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