Principle-Of-Inheritance-And-Variation Question 614

Question: Based on Lyon’s hypothesis, what will be the number of Barr bodies found in a human female suffering from Down’s syndrome [AIEEE 2004]

Options:

A) 0

B) 1

C) 2

D) 3

Show Answer

Answer:

Correct Answer: B

Solution:

Down?s syndrome is a chromosomal abnormality in humans and is associated with an extra chromosome 21 (i.e.

chromosomal formula is 45 + xx = 47), while one of the two x-chromosomes becomes genetically inert and heteropycnotic and forms the Barr body.

Hence human female suffering from Down?s syndrome contains (2x - 1 = 1) one Barr body.