Structural Organisation In Animals Question 92
Question: The characteristic feature of pernicious anaemia is:
Options:
A) increase in size of RBC.
B) deficiency of haemoglobin in RBC.
C) delay in maturation of erythroblasts.
D) None of the above
Show Answer
Answer:
Correct Answer: A
Solution:
Pernicious anaemia is a chronic illness, caused by impaired absorption of vitamin $ B_{12} $ needed to make enough healthy red blood cells.
When there is folic acid and vitamin.
$ B_{12} $ deficiency, the pro-erythroblasts of the bone marrow do not mature into normoblasts, instead, they give rise to immature cells called megaloblasts which lose their nuclei and appear as large RBC, called macrocytic.
In the peripheral circulation, therefore, we find RBC smaller than normal.
BETA
