Biomolecules Question 170
Question: The reagent which forms crystalline osazone derivative when reacted with glucose, is
[CPMT 1990]
Options:
A) Fehling solution
B) Phenylhydrazine
C) Benedict solution
D) Hydroxylamine
Show Answer
Answer:
Correct Answer: B
Solution:
$ \begin{matrix} \underset{|}{\mathop{CHO}} \\ \underset{|}{\mathop{CHOH}} \\ \underset{|}{\mathop{{{(CHOH)}_3}}} \\ CH_2OH \\ \end{matrix}\underset{Warm}{\mathop{\xrightarrow{NH_2NHC_6H_5}}}\underset{\text{Glucose phenylhydrazone}}{\mathop{\begin{matrix} \underset{|}{\mathop{CH=N-NHC_6H_5}} \\ \underset{|}{\mathop{CHOH}} \\ \underset{|}{\mathop{{{(CHOH)}_3}}} \\ CH_2OH \\ \end{matrix}}} $
$ \xrightarrow{NH_2NHC_6H_5}\begin{matrix} \underset{|}{\mathop{CH}}=N-NHC_6H_5 \\ \underset{|}{\mathop{C=O}} \\ \underset{|}{\mathop{{{(CHOH)}_3}}} \\ CH_2OH \\ \end{matrix} $
$ \xrightarrow{NH_2NHC_6H_5}\begin{matrix} \underset{|}{\mathop{CH}}=N-NHC_6H_5 \\ C=N-NHC_6H_5 \\ \overset{|}{\mathop{{{(CHOH)}_3}}} \\ \underset{Glucosazone}{\mathop{\overset{|}{\mathop{CH_2OH}}}} \\ \end{matrix} $
$ +C_6H_5NH_2+NH_3 $
BETA
