Biomolecules Question 199

Question: Assume that a particular amino acid has an isoelectric point of 6.0. In a solution at pH 1.0, which of the following species will predominate-

Options:

A) $ H_3\overset{+}{\mathop{N}}\overset{R}{\mathop{\overset{|}{\mathop{C}}}}HCO_2H $

B) $ H_2\overset{{}}{\mathop{N}}\overset{R}{\mathop{\overset{|}{\mathop{C}}}}HCO_2H $

C) $ H_3\overset{+}{\mathop{N}}\overset{R}{\mathop{\overset{|}{\mathop{C}}}}HCO_2 $

D) $ H_2\overset{{}}{\mathop{N}}\overset{R}{\mathop{\overset{|}{\mathop{C}}}}HCO_2^{-} $

Show Answer

Answer:

Correct Answer: A

Solution:

[a] In acidic medium Zwitter ion convert into

$ \overset{+}{\mathop{N}}H_3-\underset{R}{\mathop{\underset{|}{\mathop{C}}}}H-CO{O^{-}}+{H^{+}} $

$ \xrightarrow{{}}\overset{+}{\mathop{N}}H_3-\underset{R}{\mathop{\underset{|}{\mathop{C}}}}H-COOH $