Biotechnology Principles And Processes Ques 49

49. Choose the correct pair from the following [2020]

(a) Polymerases - Synthesize DNA strands

(b) Nucleases - Cut the two strands of DNA

(c) Exonucleases - Make cuts at the ends of DNA strands

(d) Ligases - Join the two DNA molecules

Show Answer

Answer : a

Hints & Solutions

(a) Ligases join the two DNA molecules. DNA ligase is an enzyme which can connect two strands of DNA together by forming a bond between the phosphate group of one strand and the deoxyribose group on another. It is used in cells to join together the Okazaki fragments which are formed on the lagging strand during DNA replication. DNA Ligase I Deficiency Leads to ReplicationDependent DNA Damage and Impacts Cell Morphology without Blocking Cell Cycle Progression.