Digestion And Absorption Ques 1

1. The enzyme enterokinase helps in conversion of

(a) trypsinogen into trypsin

(b) caseinogen into casein

(c) pepsinogen into pepsin

(d) protein into polypeptides

Show Answer

Answer : a

Hints & Solution

(a) The correct option is (a) because trypsinogen is activated by an enzyme, enterokinase, secreted by the intestinal mucosa into active trypsin. Trypsinogen is a zymogen from pancreas. Enterokinase is a sequence-specific protease that activates trypsinogen (276000) and has a major role in protein digestion. Deficiency of enterokinase is an autosomal recessive disorder characterized by severe protein malabsorption in early infancy, with failure to thrive, chronic diarrhea, and generalized edema.