Digestion And Absorption Ques 1
1. The enzyme enterokinase helps in conversion of
(a) trypsinogen into trypsin
(b) caseinogen into casein
(c) pepsinogen into pepsin
(d) protein into polypeptides
Show Answer
Answer : a
Hints & Solution
(a) The correct option is (a) because trypsinogen is activated by an enzyme, enterokinase, secreted by the intestinal mucosa into active trypsin. Trypsinogen is a zymogen from pancreas. Enterokinase is a sequence-specific protease that activates trypsinogen (276000) and has a major role in protein digestion. Deficiency of enterokinase is an autosomal recessive disorder characterized by severe protein malabsorption in early infancy, with failure to thrive, chronic diarrhea, and generalized edema.