Human Health And Diseases Ques 35

35. HIV that causes AIDS, first starts destroying:

(a) Leucocytes

(b) Helper T- Lymphocytes

(c) Thrombocytes

(d) B- Lymphocytes

Show Answer

Answer : b

Hints & Solutions

(b) After infection, HIV starts to destroy the T-cells (T-helper lymphocytes). T cells are very important for the immune system. In the early stage of infection, the decline in numbers of $T$ cells is observed. Immunosuppression is caused due to HIV infection is a resultant of several factors including defective innate signalling pathways, increased viral replication and virus load, gradual loss of peripheral CD4 $+T$ cells and depletion of $T$ lymphocytes at mucosal sites that collectively lead to progressive immune deficiency results in AIDS.



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