Molecular Basis Of Inheritance Ques 19

19. Which enzymes will be produced in a cell in which there is a nonsense mutation in the lac Y gene?

(a) Lactose permease

(b) Transacetylase

(c) Lactose permease and transcetylase

(d) $\beta$ - galactosidase

Show Answer

Answer : d

Hints & Solution

(d) A nonsense mutation is the one which stops polypeptide synthesis due to formation of a terminating or nonsense codon e.g. ATT (UAA), ATG (UAG), ACT (UGA). The lactose or lac operon of Escherichia coli contains structural genes $(z, y, a)$. If y codes for termination of polypeptide chain then only the product of ’ $z$ ’ gene transcribe to form $\beta$ galactosidase.



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