Principles Of Inheritance And Variation Ques 160

160. Down’s syndrome is caused by an extra copy of chromosome number 21. What percentage of offspring produced by an affected mother and a normal father would be affected by this disorder?

25%

(b) 100%

75%

50%

Show Answer

Answer : d

Hints & Solution

(d) 50% of ova will have $(n+1)$ chromosomes which would, on fertilisation, yield abnormal zygotes $(n+1)+(n)=2n+1$.