Principles Of Inheritance And Variation Ques 67

67. At a particular locus, frequency of ’ $A$ ’ allele is 0.6 and that of ’ $a$ ’ is 0.4 . What would be the frequency of heterozygotes in a random mating population at equilibrium?

(a) 0.36

(b) 0.16

(c) 0.24

(d) 0.48

Show Answer

Answer : d

Hints & Solution

(d) The mathematical expression to calculate allele frequency can be given as $p+q=1$. Where $p$ represents the frequency of dominant allele and q represents the frequency of recessive allele. The bionomial expression of Hardy Weinberg’s law to calculate genotype frequency is $p^{2}+2 pq+q^{2}=1$ where $p^{2}=$ homozygous dominant $2 pq=$ heterozygous dominant $q^{2}=$ homozygous recessive. Frequency of heterozygous individuals $=2 \times 0.6 \times 0.4=0.48$.



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