Amines Ques 46

46. Which of the following reactions is appropriate for converting acetamide to methanamine?

[2017]

(a) Hoffmann hypobromamide reaction

(b) Stephens reaction

(c) Gabriels phthalimide synthesis

(d) Carbylamine reaction

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Answer:

Correct Answer: 46.(a)

Solution:

It is called Hoffmann Bromamide reaction.

Hoffmann bromamide reaction: Reaction of an acid amide with bromine in an aqueous or ethanolic solution of sodium hydroxide to form a primary amine, with one carbon atom less, is known as Hoffmann bromamide reaction.